《那把柳叶刀:剥下医学的外衣》主体内容由50个左右小主题组成。每个小题目都是选取自医学发展历程中代表性的、非医学专业读者也都知道一些的医药科技发明、事件等作为切入点，成为一个选题。根据内容特点，书稿分为史海钩沉（事件）、科技的脚步、工具寻踪、另类医史等几部分。
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